Re-usable Nitrous Oxide Inhaler


Reduce Anxiety and Pain in Seconds

for Adults and Children


"Can be administered while waiting for a procedure, immediately before the procedure or during the procedure."


Each dose refill delivers an average of 39.6% nitrous oxide over approximately 180 seconds.  Each dose comes with a disposable gas cylinder and mask.

 CE 650446

ISO 13485 Certified FM 650454

Health Canada 99099

Human Use: Available Outside USA Only

Veterinarian Use: Available Everywhere 

For painful or uncomfortable exams or office procedures such as botox injections, cystoscopies, vasectomies, mole removal, local injections, vaccinations and other medical office procedures.




Indications for Use:

Hand-Held Nitrous® is intended to create short term supplemental analgesia to patients undergoing minor procedures by delivering a limited 16 grams (8.6 liters) of nitrous oxide over a total of 180 seconds of inhalation time. The effects of the gas are limited to approximately five (5) minutes and are not intended to last the entire length of the procedure.



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Mask Design: Ready Mode (Complete with Cylinder & Mask)






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Benefits of Hand-Held Nitrous®

  • Creates short term pain and anxiety reduction in seconds
  • Safe and Effective
  • Patients recover in minutes
  • Tiny - fits in the pocket
  • Patient can stop inhalation any time
  • Easy to administer
  • No special training or certification required
  • Inexpensive
  • Powerful
  • Uses no electricity or batteries
  • Safe for administrator: Meets all OSHA and NIOSH exposure limits
  • No special evacuation plumbing required for the office
  • Uses USP medical grade nitrous oxide
    • Approved under FDA New Drug Application 208069
  • Dispenser can be used up to 150 times
  • Licensed in the State of Texas
    • Medical Device Manufacturer No.: 1001227
    • Wholesale Distributor of Prescription Drugs No.: 1001252


Clinical Study

FDA Approval for Hand-Held Nitrous Gas

Common Questions

Hand-Held Nitrous Easy-Step Instructions

Instructions for Use (Mask)

Instructions for Use (Mouth Piece)

Instructions for Use (Veterinarian)


When I use Hand-Held Nitrous® my patients experience significantly reduced pain, discomfort, and stress. Hand-Held Nitrous® is a great addition to my practice.

Dr. Robert P. Schmid

Plastic Surgeon


Any time I can improve the patient experience my practice becomes more successful. I use Hand-held Nitrous® because it dramatically improves patient satisfaction.

Dr Howard Beck